MFAP3L predicts tumor microenvironment status, molecular subtypes and clinical benefit in patients with bladder cancer

Abstract Bladder cancer (BLCA), ranking as the tenth most prevalent malignancy globally, imposes a substantial public health and socio-economic challenge.Despite ongoing efforts by urologists to identify novel molecular subtypes and treatment paradigms, the intrinsic heterogeneity of BLCA continues to obstruct the efficacy of current diagnostic and

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Simultaneous Vitreoretinal Surgery and Penetrating Keratoplasty without a Keratoprosthesis or Endoscopy for Vitreoretinal Disease Associated with Corneal Opacity

We evaluated the visual outcome of combined penetrating keratoplasty (PKP) and 25G pars plana vitrectomy (PPV) performed without a temporary keratoprosthesis or endoscopy in a patient with vitreoretinal disease complicated by severe corneal opacity.The patient was a 68-year-old woman who had severe corneal opacity and silicone oil in her left eye a

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FO Model Checking of Interval Graphs

We study the computational ttc flame red switches complexity of the FO model checking problem on interval graphs, i.e., intersection graphs of intervals on the real line.The main positive result is that FO model checking and successor-invariant FO model checking can be solved in time O(n log n) for n-vertex interval graphs with representations cont

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